Guerneville, California

Population 4,536

This Sonoma County town makes a perfect home base for a wine tasting road trip. You can opt to stay in a traditional property like the Creekside Inn (creeksideinn.com), which offers the wheelchair-accessible Lark Cabin with a roll-in shower; or choose to glamp in style at Russian River AutoCamp, which boasts a custom-built wheelchair-accessible unit (emerginghorizons.com/a-redwood-retreat-to-remember/). Then head out for some wine tasting at Marimar Estate Vineyards & Winery (www.marimarestate.com) — which offers good wheelchair access. Top off your visit with a stroll through the redwoods at Armstrong Redwoods State Park (emerginghorizons.com/a-trail-for-everyone-at-armstrong-redwoods/), which has several wheelchair-accessible trails.